Dr. David Scott is very active in the field of orthopaedic surgery and joint replacement research. He believes that research is critical to the advancement of medicine and necessary for improving the care and solutions we offer our patients.
Dr. Scott is a leader in the research field and is one of the most active physicians in joint replacement research in the region. He initiates many of his own studies, which is unique among his peers. He recognizes that physician-driven research is critical for finding new and better ways to serve patients. Dr. Scott has a strong team supporting this important research. The full team at OSC maintains certifications with The National Institute of Health and The Collaborative Institutional Training Initiative. In addition, Dr. Scott has been a leader in technology design and continues to help design some of the tools that are shaping orthopaedics today. Some of his work has included development of a state-of-the-art knee replacement system. His commitment to research expands into the academic world and helps shape the future of the profession. He is on the academic staff at both the University of Utah and the University of Washington.
Current Research (Actively Enrolling)
- Medacta GMK Sphere Medial-Pivot, Cruciate Substituting vs. Medacta GMK PS Posterior Stabilized Knee Outcomes Study.
- Medacta GMK Sphere Medial-Pivot, Cruciate Substituting Multi-Center, Post-Market Outcomes Study.
- Antero-Posterior Knee Stability with Medial-pivot, Cruciate-Substituting, and Posterior-Stabilized Total Knee Arthroplasty. A Retrospective Study.
- An Open-Label, Non-Controlled Study to Evaluate Outcomes of Pulsed Electromagnetic Field (PEMF) Therapy in Subjects with Various Pain Etiologies.
Ongoing Studies (Enrollment is Closed)
- A Prospective Comparison of Total Knee Arthroplasty with the OMNI Apex Ultracongruent vs. the Triathlon CS Tibial Insert vs. the Triathlon PS Tibial Insert.
- A DXA Evaluation of Bone Density Changes After Hip Replacement. Performance of the OMNI Apex Modular Hip Stem and the OMNI Apex Arc Stem in Primary Total Hip Arthroplasty. Five Year Clinical and DXA Analysis.
- A Dual Energy X-Ray Absorptiometry Comparison of Periprosthetic Bone Loss Between Patients Undergoing Hip Resurfacing Surgery and Total Hip Arthroplasty.
Past Research Projects
A multi-centre, parallel, double-blind, blinded evaluator, randomized placebo controlled study to evaluate the safety and effectiveness of a new viscoelastic hydrogel in the treatment of knee osteoarthritis with an open label extension.
A prospective, matched case comparison of total knee arthroplasty in comparison with pain/motion knee society scores of subjects implanted with different knee devices.
A dual energy x-ray absorptiometry (DXA) evaluation of bone density changes after hip replacement. To analyze bone mineral density measurements with the performance of a Modular hip stem vs a novel neck-sparing device in primary total hip arthroplasty.
A dual energy x-ray absorptiometry (DXA) comparison of periprosthetic bone loss between patients undergoing lessinvasive hip resurfacing surgery vs total hip arthroplasty.
This study is being done to determine if Zoledronic Acid (Zometa) is effective in preventing bone loss commonly seen after total hip replacement surgery. Bone mineral density is also being measured at several intervals in the seven gruen zones of the proximal femur by a dual energy x-ray apsorptiometry (DXA). Not enrolling.
This study is a long-term ongoing follow-up study. At annual visits after total hip replacement surgery, the patient’s bone mineral density is measured to evaluate the general status of their bone density using a spinal and orthopaedic hip DXA scan. This study was initiated by Dr. David Scott.
This study is investigating the use of risedronate (Actonel) in reducing bone loss in the femur, which is caused by total hip replacement surgery. Bone loss is determined by measuring the patient’s bone mineral density at several intervals after the operation. We have finished enrolling patients in this study. Patients were initially followed for two years, and we recently obtained approval to continue following patients in this study for an additional three years. This study was initiated by Dr. David Scott with funding from Procter & Gamble.
Patients who enrolled in this study were implanted with one of two different hip stems. The two stems had different designs and were made of different materials. Each patient’s bone mineral density was measured at several intervals after surgery to investigate whether implantation of one of the stems resulted in less bone loss after total hip replacement surgery, as compared to the other. We have finished enrolling patients in this study. This study was initiated by Dr. David Scott in conjunction with Dr. William Jaffe at the University of Utah.
This study compared bone loss caused by total hip replacement surgery in patients implanted with either a composite stem or a titanium stem. Bone mineral density was measured at several intervals after surgery using dual energy x-ray absorptiometry to determine the amount of bone loss. We have finished enrolling patients in this study. Patients are being followed for two years following total hip replacement surgery. This study was initiated by Dr. David Scott with funding from Zimmer.
This study compared the efficacy of fondaparinux sodium (Arixtra) given either the day of surgery or the morning after surgery in preventing deep blood clots in patients after total knee replacement surgery. We have finished enrolling patients in this study. This study was sponsored by Organon Sanofi-Synthelabo.
This study investigated the efficacy of dalteparin sodium (Fragmin) as compared to warfarin in preventing deep blood clots after total knee replacement surgery. We have finished enrolling patients in this study. This study was sponsored by Pfizer Pharmaceutical Company.
Most total hip replacements use a metal or ceramic “ball” attached to a metal stem and a metal socket with a plastic liner. In this study the hip replacement parts are a ceramic ball with metal shell insert or a metal ball with a metal shell insert. This study is being done to find out if the ceramic ball and metal liner hip implant will last as long or longer than the metal ball and metal liner hip implant. We have finished enrolling patients in this study but a two year follow-up is continuing. This study was sponsored by DePuy Orthopaedics Inc.
Dr. Scott was one of a group of principal investigators who participated in this industry-sponsored study involving patients undergoing a total hip replacement. The purpose of this study was to determine if the study device was safe and effective in treating pain following surgery. This study device which contained fentanyl was worn on the skin like a patch and the patient could control dosing by pushing a button located on the device. The study device was compared to a standard treatment called morphine intravenous patient-controlled analgesia (IV PCA) pump. We have finished enrolling patients in this study. This study was sponsored by Ortho McNeil Pharmaceutical Inc.
The NaviPro Image-Free navigation system was designed to provide feedback to the surgeon on limb alignment and implant position during surgery. The primary objective of this study was to evaluate the accuracy of the NaviPro™ Image-Free™ navigation system in total hip and total knee replacement surgery and to further develop the NaviPro navigation software in a clinical environment to improve ease of use from the perspective of the surgeon and operating room staff. We have finished enrolling patients in this study. This study was sponsored by Kinamed, Inc.
Spokane Joint Replacement Center was one of 200 multi-national sites (including locations in the United States, Canada and Mexico) comparing two different doses of dabigatran etexilate (an oral anti-coagulant) and Lovenox® in a parallel group/double blind design. Dr David Scott is one of a group of principal investigators overseeing a portion of the 2,610 total patients who were divided into three groups receiving two different doses of study drug capsules and injections. We have finished enrolling patients in this study. This study was sponsored by Boehringer-Ingelheim pharmaceuticals.
Publications by Dr. David F. Scott
Posterior Stabilized Versus Cruciate-Substituting Total Knee Arthroplasty: Midterm Results. David F. Scott, MD. The Journal of Arthroplasty, Vol 29, No 9, 2014: 179-181. (Presentation to AAHKS.)
Femoral Bone Mineral Density Loss After Short Stem Neck-Sparing, Resurfacing, and Conventional Hip Arthroplasty. David F. Scott, MD. J Bone Joint, vol. 95-B no. SUPP 34, 2013: 525.
Posterior Stabilized Versus Cruciate-Substituting Total Knee Arthroplasty: Midterm Results. David F. Scott, MD. J Bone Joint vol. 95-B no. SUPP 34, 2013: 526.
Effect of Zoledronic Acid on Reducing Femoral Bone Mineral Density Loss following Total Hip Arthroplasty. Preliminary Results of a Prospective Randomized Trial. David F. Scott, Jennifer N. Woltz, Rachel R. Smith. The Journal of Arthroplasty, Vol 28, No. 4, 2013: 671-675.
Cementless Total Knee Arthroplasty Handbook, Surgical Techniques in Total Knee and Revision Arthroplasty. Aaron A. Hofmann, David F. Scott. Editors, Giles R. Scuderi, Alfred J. Tria, Jr. Springer, 2006 Chapter 1.
Cementless Total Knee Arthroplasty, Fixation: Cementless. Aaron A. Hofmann, David F. Scott. Surgical Techniques in Total Knee Arthroplasty. Giles R. Scuderi and Alfred J. Tria, Editors, Springer-Verlag, 2002 Chapter 35. New York, due 1/99, ISBN 0-387-98389-9.
Long-Term Follow-Up of High Tibial Osteotomy with a Calibrated Osteotomy Guide, Rigid Internal Fixation and Early Motion. Annette Billings, David F. Scott, Marcelo P. Camargo, Aaron A. Hofmann. Journal of Bone and Joint Surgery, 2000 Jan: 82(1): 70-9.
The Effect of Surface Roughness on the Stress Adaptation of Trabecular Architecture Around a Cylindrical Implant. Luo, G.M., Sadegh, A.M., Alexander, H., Jaffe, W., Scott, D., Cowin, S.C. Journal of Biomechanics, 32, 1999: 275-284.
Postmortem Retrieval Analysis of Metal-Backed Patellae in Total Knee Replacements. Roy D.
Bloebaum, Kent N. Bachus, Jennifer W. Jensen, David F. Scott, Aaron A. Hofmann. Journal of Bone and
Joint Surgery, Vol. 80-A, 1998: 518-528.
Total Hip Arthroplasty with Hydroxyapatite – Coated Prosthesis. Current Concepts Review. William L. Jaffe, David F. Scott. Journal of Bone and Joint Surgery, Vol. 78-A, 1996: 1918-1935.
Host Bone Response to Porous – Coated Cobalt-Chrome and Hydroxyapatite-Coated Titanium Femoral Components in Hip Arthroplasty. Dual Energy X-Ray Absorptiometry Analysis of Paired Bilateral Cases of Five to Seven Years. David F. Scott, William L. Jaffe. Journal of Arthroplasty, Vol. 11, No. 4, 1996: 429-437.
A Comparison of Blood Loss and Transfusion Requirements in Total Knee Arthroplasty with and without Arterial Tourniquet. Kenneth L. Jarolem, David F. Scott, William L. Jaffe, Kenneth Shuben Stein, Fredrick F. Jaffe and Ted Atik. American Journal of Orthopedics, Vol. 24, No. 12, 1995: 906-909.
Fracture Blister Formation: A Laboratory Study. Carl P. Giordano, David F. Scott, Kenneth J. Koval, Frederick Kummer, Ted Atik, Panna Desai. Journal of Trauma, Vol. 38, No. 6, 1995: 907-909.
Effects of Texturing Techniques on Surface Composition of Metal Orthopaedic Implants. John L. Ricci, Fred J. Kummer, David F. Scott, David I. Pedowitz, Robert S. Casar, Harold Alexander. Surface Modification Technologies VII, Proceedings of the Seventh International Conference, Sanjo, Niigata, Japan, edited by T.S. Sudarshan, K. Ishizaki, M. Takata and K. Kamata, The Institute of Materials, 1994.
Rationale and Clinical Application of Hydroxyapatite Coatings in Pressfit Total Hip Arthroplasty. William L. Jaffe, David F. Scott. Seminars in Arthroplasty, Vol. 4, No. 3 (July) 1993: 159-166.
If you’re interested in reading about other orthopaedic research, these resources may be useful.
American Academy of Orthopaedic Surgeons (AAOS)
AAOS is your source for the latest legislative, educational, healthcare policy, and research information.
American Association of Hip and Knee Surgeons
This professional organization comprises more than 900 surgeons in the U.S. and Canada who devote fifty percent or more of their practice to total joint replacement.
Journal of the American Academy of Orthopaedic Surgeons
The official peer-reviewed journal of the American Academy of Orthopaedic Surgeons. Read abstracts of articles online.
The largest private, not-for-profit contributor to arthritis research in the world, providing public health education, pursuing public policy and legislation, and conducting evidence-based programs.
Arthroscopy Association of North America (AANA)
Promoting, encouraging, supporting, and fostering the development and dissemination of knowledge in the discipline of arthroscopic surgery through continuing medical education functions.
International Society for Computer Assisted Orthopaedic Surgery
A non-profit organization bringing together individuals throughout the world who have indicated or are indicating interest in computer-assisted orthopaedic surgery.
Joint Implant Surgery & Research Foundation
Specializing in clinical and surgical orthopedic study groups, and product development for the advancement of total hip, knee, and shoulder surgery.
Journal of Arthroplasty
The American Association of Hip and Knee Surgeons’ peer-reviewed journal which publishes original research and manuscripts from all areas relating to joint replacement or the treatment of its complications.
Journal of Bone and Joint Surgery
Journal covering topics related to bone and joint surgery. Read abstracts of articles online.
Orthopaedic Research Society
Read the organization’s newsletter, past and current issues of the Journal of Orthopaedic Research and more.
Read current and back issues of Orthopedics Today written for orthopedic surgeons.